Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557497 | 0.90 | HPGD (0.49) | ABCB1POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8174989 | 0.89 | POLB (0.50) | POLBCYP3A4CYP2C9KMT2A | |
| SCHEMBL9557966 | 0.88 | CES2 (0.50) | POLBCYP3A4MEN1KMT2A | |
| SCHEMBL9557283 | 0.88 | CES2 (0.50) | POLBCYP3A4MEN1KMT2A | |
| SCHEMBL9557177 | 0.84 | HPGD (0.53) | ABCB1POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9558207 | 0.84 | ACLY (0.44) | ABCB1POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9558162 | 0.82 | HPGD (0.48) | ABCB1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9558129 | 0.81 | CES2 (0.47) | POLBCYP3A4CYP2C9MEN1KMT2A | |
| SCHEMBL9557769 | 0.81 | ABCB1 (0.45) | ABCB1POLBCYP3A4 | |
| SCHEMBL9557162 | 0.80 | ALDH1A1 (0.43) | MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |