Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | YAP1 | P46937 | 2/20 | 0.65 |
| ▸ | STS | P08842 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165580 | 1.00 | MAPK1 (0.75) | MAPK1KMT2AYAP1STSATM | |
| SCHEMBL6162914 | 0.89 | MAPK1 (0.62) | MAPK1KMT2AYAP1STSATM | |
| SCHEMBL6162909 | 0.89 | MAPK1 (0.62) | MAPK1KMT2AYAP1STSATM | |
| SCHEMBL7276597 | 0.85 | POLB (0.65) | MAPK1KMT2AYAP1ALDH1A1POLB | |
| SCHEMBL7276592 | 0.85 | POLB (0.65) | MAPK1KMT2AYAP1ALDH1A1POLB | |
| SCHEMBL9558236 | 0.84 | MAPK1 (0.64) | MAPK1KMT2AYAP1STSATM | |
| SCHEMBL9558243 | 0.83 | YAP1 (0.64) | MAPK1KMT2AYAP1ATMMEN1 | |
| SCHEMBL6160782 | 0.82 | MEN1 (0.73) | MAPK1KMT2AMEN1 | |
| SCHEMBL6162223 | 0.82 | MEN1 (0.73) | MAPK1KMT2AMEN1 | |
| SCHEMBL2633263 | 0.82 | LMNA (0.69) | MAPK1KMT2ALMNATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |