Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486619 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TDP1 | |
| SCHEMBL5711158 | 0.73 | FFAR3 (0.44) | TSHRALDH1A1TDP1 | |
| SCHEMBL10545589 | 0.72 | TSHR (0.50) | TSHRALDH1A1TP53 | |
| SCHEMBL9661307 | 0.71 | ALOX15 (0.33) | ALDH1A1TP53TDP1 | |
| SCHEMBL8789218 | 0.69 | — | — | |
| SCHEMBL8961709 | 0.67 | TSHR (0.46) | TSHRALDH1A1 | |
| SCHEMBL128808 | 0.67 | FFAR3 (0.44) | TSHRALDH1A1TDP1 | |
| SCHEMBL1331563 | 0.66 | — | — | |
| SCHEMBL11172685 | 0.66 | — | — | |
| SCHEMBL35516 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260424-A | B-(keto or sulfonyl) esters from reaction of silylketene acetal and acyl or sulfonyl compound | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-11-09 | — | — | US | disclosed |
| US-5110869-A | Block polymerization, endcapping, coupling, chain extension | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-05 | — | — | US | disclosed |
| US-4983679-A | ENDCAPPING, COUPLING, CHAIN EXTENSION OF POLYMERS | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0272285-A4 | ACYLATION AND SULFONATION OF SILYLKETENE ACETALS. | DU PONT (US) | 1990-04-10 | — | — | EP | disclosed |
| EP-0272285-A1 | ACYLATION AND SULFONATION OF SILYLKETENE ACETALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-29 | — | — | EP | disclosed |
| WO-1987007265-A1 | ACYLATION AND SULFONATION OF SILYLKETENE ACETALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-03 | — | — | WO | disclosed |