SCHEMBL9558709

SCHEMBL9558709

CCCc1nc(-c2ccccc2)c(C(=O)Cc2ccc(-c3ccccc3C(=O)O)cc2)[nH]1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRS3 P32247 7/20 0.50
PPARG P37231 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6534729 0.82 BRS3 (0.57) BRS3
SCHEMBL10902221 0.74 LTB4R2 (0.60) BRS3PPARG
SCHEMBL3230323 0.74 LTB4R2 (0.63) BRS3PPARG
SCHEMBL8330248 0.73 AGTR1 (0.43) BRS3PPARG
SCHEMBL11050965 0.72 ADORA3 (0.51) PPARG
SCHEMBL6005830 0.69 AGTR1 (0.59) PPARG
SCHEMBL9251216 0.69 AGTR1 (0.36)
Hexane SCHEMBL9090054 0.69 LTB4R2 (0.64) BRS3PPARG
SCHEMBL3906504 0.69 BRS3 (0.70) BRS3
SCHEMBL9304542 0.69 BRS3 (0.56) BRS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0533840-A1 TREATMENT OF CHRONIC RENAL FAILURE WITH IMIDAZOLE ANGIOTENSIN-II RECEPTOR ANTAGONISTS. DU PONT (US) 1993-03-31 EP claimed