Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 5/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9452733 | 0.88 | BRS3 (0.56) | BRS3AGTR1AGTR2 | |
| SCHEMBL9529409 | 0.87 | BRS3 (0.55) | BRS3AGTR1AGTR2 | |
| SCHEMBL9510826 | 0.86 | BRS3 (0.55) | BRS3AGTR1AGTR2 | |
| SCHEMBL9452730 | 0.82 | BRS3 (0.57) | BRS3AGTR1AGTR2 | |
| SCHEMBL9756381 | 0.79 | KDM4E (0.51) | BRS3 | |
| SCHEMBL8741191 | 0.78 | BRS3 (0.47) | BRS3AGTR1AGTR2 | |
| SCHEMBL8060271 | 0.78 | BRS3 (0.59) | BRS3AGTR1AGTR2 | |
| SCHEMBL6279332 | 0.78 | PPARG (0.55) | BRS3AGTR1AGTR2 | |
| SCHEMBL3211177 | 0.78 | PPARG (0.47) | BRS3AGTR1 | |
| SCHEMBL1227544 | 0.77 | BRS3 (0.55) | BRS3AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354766-A | 2-Ethoxy-1-((2'(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl) biphenyl-4-yl)methyl)benzimidazole-7-carboxylic acid; hypotensive agents; CNS activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |