Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 13/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 12/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 12/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.47 |
| ▸ | CFB | P00751 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7112481 | 0.83 | ADRA2B (0.47) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL7047648 | 0.78 | TAAR1 (0.56) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL7045608 | 0.77 | TAAR1 (0.46) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL7043901 | 0.77 | TAAR1 (0.43) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL2754359 | 0.75 | HSD17B10 (0.51) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL14380995 | 0.74 | CFB (0.45) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL1852745 | 0.73 | CFB (0.49) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL7046036 | 0.72 | TAAR1 (0.57) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL11185255 | 0.71 | PTGS2 (0.47) | ADRA2AADRA2BADRA2CADRA1ACYP3A4 | |
| SCHEMBL7048853 | 0.71 | TAAR1 (0.52) | ADRA2AADRA2BADRA2CADRA1ACFB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196531-A | Poly(N-cyclic iminoether), process for production thereof, thermosetting composition containing it and thermoset resin | TEIJIN LIMITED (JP) | 1993-03-23 | — | — | US | disclosed |