Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 7/20 | 0.43 |
| ▸ | BRD4 | O60885 | 5/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059320 | 0.82 | CREBBP (0.45) | CREBBPBRD4HTTLMNATSHR | |
| SCHEMBL8809394 | 0.74 | CREBBP (0.54) | CREBBPBRD4HTTPDE4APDE4B | |
| SCHEMBL10702878 | 0.74 | BRD4 (0.47) | CREBBPBRD4GAADDB1CRBN | |
| SCHEMBL9559119 | 0.73 | DDB1 (0.38) | CREBBPBRD4LMNATSHRDDB1 | |
| SCHEMBL9670907 | 0.71 | PSEN1 (0.44) | MAOBGAADDB1CRBN | |
| SCHEMBL6866934 | 0.70 | TSHR (0.55) | CREBBPBRD4TSHRGAADDB1 | |
| SCHEMBL9660776 | 0.70 | TSHR (0.44) | CREBBPBRD4HTTLMNATSHR | |
| SCHEMBL4695211 | 0.70 | TSHR (0.55) | CREBBPBRD4TSHRGAADDB1 | |
| SCHEMBL10582642 | 0.70 | TSHR (0.44) | CREBBPBRD4HTTLMNATSHR | |
| SCHEMBL7263768 | 0.70 | TSHR (0.55) | CREBBPBRD4TSHRGAADDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5239113-A | Anticoagulants | MONSANTO COMPANY (US) | 1993-08-24 | — | — | US | disclosed |