Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559694 | 0.92 | NR1H2 (0.30) | — | |
| SCHEMBL9559622 | 0.85 | TP53 (0.39) | NPC1TP53TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9559741 | 0.84 | NPC1 (0.38) | NPC1TP53TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9559558 | 0.79 | TDP1 (0.41) | NPC1TP53TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9559638 | 0.78 | TAAR1 (0.31) | — | |
| SCHEMBL9547382 | 0.75 | GSK3B (0.32) | RAB9AALDH1A1HTT | |
| SCHEMBL9559574 | 0.75 | NPC1 (0.39) | NPC1TP53TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL4734052 | 0.74 | LMNA (0.38) | TP53ALDH1A1HTT | |
| SCHEMBL9559621 | 0.74 | KMT2A (0.49) | SMN1; SMN2CYP19A1MAPTTHRBALDH1A1 | |
| SCHEMBL9559629 | 0.72 | IDO1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5235061-A | 2,4-disilaalkanes; agriculture | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1993-08-10 | — | — | US | disclosed |