Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | BAD | Q92934 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559560 | 0.98 | ACHE (0.36) | ACHEPDPK1MEN1POLBKMT2A | |
| SCHEMBL9559536 | 0.91 | MAOB (0.31) | PTGS1PTGS2MAOB | |
| SCHEMBL15757626 | 0.91 | LMNA (0.34) | TTRHTTALDH1A1 | |
| SCHEMBL9559670 | 0.85 | ADORA1 (0.36) | ACHEPDPK1MEN1POLBKMT2A | |
| SCHEMBL9559625 | 0.85 | ADORA1 (0.36) | ACHEPDPK1MEN1POLBKMT2A | |
| SCHEMBL9559721 | 0.83 | ADORA1 (0.36) | ACHEMEN1KMT2AALDH1A3PTGS1 | |
| SCHEMBL10416339 | 0.81 | RAB9A (0.38) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL9559594 | 0.79 | NPC1 (0.43) | KDM4EHPGDHTTNPSR1ALDH1A1 | |
| SCHEMBL9559602 | 0.77 | NPC1 (0.44) | KDM4ECYP1A2HPGDCYP2C19HTT | |
| SCHEMBL9559593 | 0.76 | MEN1 (0.31) | MEN1POLBKMT2AALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5235061-A | 2,4-disilaalkanes; agriculture | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1993-08-10 | — | — | US | disclosed |