Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 19/20 | 0.76 |
| ▸ | RARB | P10826 | 10/20 | 0.76 |
| ▸ | RARA | P10276 | 9/20 | 0.76 |
| ▸ | RXRA | P19793 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL955370 | 0.99 | RARG (0.75) | RARGRARBRARARXRA | |
| SCHEMBL956218 | 0.97 | RARG (0.75) | RARGRARBRARARXRA | |
| SCHEMBL959274 | 0.94 | RARG (0.74) | RARGRARBRARARXRA | |
| SCHEMBL956914 | 0.93 | RARG (0.65) | RARGRARBRARARXRA | |
| SCHEMBL958956 | 0.92 | RARG (0.72) | RARGRARBRARARXRA | |
| SCHEMBL955172 | 0.91 | RARG (0.68) | RARGRARBRARARXRA | |
| SCHEMBL958466 | 0.91 | RARG (0.68) | RARGRARBRARARXRA | |
| SCHEMBL955171 | 0.90 | RARG (0.67) | RARGRARBRARARXRA | |
| SCHEMBL958855 | 0.90 | RARG (0.61) | RARGRARBRARARXRA | |
| SCHEMBL4654752 | 0.90 | RARG (0.61) | RARGRARBRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160310439-A1 | LIPID MICROCAPSULES PREFERABLY COMPRISING A RETINOID, AND COMPOSITION CONTAINING SAME, METHOD FOR THE PRODUCTION THEREOF, AND USE OF SAME IN DERMATOLOGY | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-10-27 | — | — | US | claimed |
| US-20150190372-A1 | MICROCAPSULES CONTAINING RETINOIDS, METHOD OF PREPARING SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2015-07-09 | — | — | US | claimed |
| US-20150125520-A1 | LIPID NANOCAPSULES COMPRISING A RETINOID, NANODISPERSION AND COMPOSITION CONTAINING THE SAME, PROCESS FOR PREPARING THE SAME AND USE THEREOF IN DERMATOLOGY | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2015-05-07 | — | — | US | claimed |
| US-20120282314-A1 | DERMATOLOGICAL/COSMETIC SKIN DEPIGMENTING COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2012-11-08 | — | — | US | claimed |
| US-7872026-B2 | Ligand activators of the RAR receptors and pharmaceutical/cosmetic applications thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-01-18 | — | — | US | claimed |
| US-20100143445-A1 | Dermatological/cosmetic skin depigmenting compositions | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-06-10 | — | — | US | claimed |
| EP-1692093-B1 | BIPHENYL DERIVATIVES USEFUL AS LIGANDS THAT ACTIVATE THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2008-11-19 | — | — | EP | claimed |
| US-20070021473-A1 | Novel ligand activators of the RAR receptors and pharmaceutical/cosmetic applications thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-01-25 | — | — | US | claimed |
| EP-4169512-A1 | DERMATOLOGICAL COMPOSITION COMPRISING OLEOSOMES AND RETINOIDS, METHOD FOR PREPARING SAME AND USE THEREOF | Galderma Research & Development (FR) | 2023-04-26 | — | — | EP | disclosed |
| CN-113559083-A | Lipid microcapsules comprising a retinoid | 盖尔德马研究及发展公司 | 2021-10-29 | — | — | CN | disclosed |
| US-10925822-B2 | Process for preparing a dermatological composition comprising oleosomes | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2021-02-23 | — | — | US | disclosed |
| US-10772807-B2 | Lipid microcapsules preferably comprising a retinoid, and composition containing same, method for the production thereof, and use of same in dermatology | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2020-09-15 | — | — | US | disclosed |
| US-10702604-B2 | Lipid nanocapsules comprising a retinoid, nanodispersion and composition containing the same, process for preparing the same and use thereof in dermatology | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2020-07-07 | — | — | US | disclosed |
| US-20160310439-A1 | LIPID MICROCAPSULES PREFERABLY COMPRISING A RETINOID, AND COMPOSITION CONTAINING SAME, METHOD FOR THE PRODUCTION THEREOF, AND USE OF SAME IN DERMATOLOGY | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-10-27 | — | — | US | disclosed |
| US-7872026-B2 | Ligand activators of the RAR receptors and pharmaceutical/cosmetic applications thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-01-18 | — | — | US | disclosed |
| US-20100143445-A1 | Dermatological/cosmetic skin depigmenting compositions | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-06-10 | — | — | US | disclosed |
| EP-1692093-B1 | BIPHENYL DERIVATIVES USEFUL AS LIGANDS THAT ACTIVATE THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2008-11-19 | — | — | EP | disclosed |
| US-20070021473-A1 | Novel ligand activators of the RAR receptors and pharmaceutical/cosmetic applications thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-01-25 | — | — | US | disclosed |
| EP-1692093-A1 | BIPHENYL DERIVATIVES USEFUL AS LIGANDS THAT ACTIVATE THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005056516-A1 | BIPHENYL DERIVATIVES USEFUL AS LIGANDS THAT ACTIVATE THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021473-A1 | Novel ligand activators of the RAR receptors and pharmaceutical/cosmetic applications thereof | RARA, RARB, RARG | RARG 3/4885RARB 2/4885RARA 1/4885 |
| US-10925822-B2 | Process for preparing a dermatological composition comprising oleosomes | LIPA, CUTA, RAB5IF | RARG 3092/4885RARB 3711/4885RARA 3351/4885 |
| US-20120282314-A1 | DERMATOLOGICAL/COSMETIC SKIN DEPIGMENTING COMPOSITIONS | TYR, RARA, MITF | RARG 6/4885RARB 5/4885RARA 2/4885 |
| US-20100143445-A1 | Dermatological/cosmetic skin depigmenting compositions | TYR, RARA, MITF | RARG 6/4885RARB 5/4885RARA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.