Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187672 | 0.75 | ALDH1A1 (0.38) | TDP1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL5605666 | 0.75 | ALDH1A1 (0.38) | TDP1ALDH1A1GLASMN1; SMN2TSHR | |
| SCHEMBL18094266 | 0.74 | TDP1 (0.37) | TDP1ALDH1A1GLAMEN1KMT2A | |
| SCHEMBL1461646 | 0.72 | TDP1 (0.40) | TDP1ALDH1A1GLAMEN1KMT2A | |
| SCHEMBL38657357 | 0.72 | TDP1 (0.45) | TDP1ALDH1A1GLAMEN1KMT2A | |
| SCHEMBL14193863 | 0.71 | TDP1 (0.47) | TDP1ALDH1A1GLAMEN1KMT2A | |
| SCHEMBL10697835 | 0.71 | ALDH1A1 (0.39) | TDP1ALDH1A1GLAMEN1KMT2A | |
| SCHEMBL9184093 | 0.69 | ALDH1A1 (0.35) | TDP1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL25293270 | 0.69 | TDP1 (0.49) | TDP1ALDH1A1GLAMEN1KMT2A | |
| SCHEMBL1949792 | 0.69 | TDP1 (0.49) | TDP1ALDH1A1GLAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5209871-A | Reacting a polyether diamine and a epoxysilane, alkali metal salt | FORD MOTOR COMPANY (US) | 1993-05-11 | — | — | US | disclosed |