SCHEMBL10697835

SCHEMBL10697835

CO[Si](CCC(C)OCC1CO1)(OC)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
GLA P06280 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
HRH3 Q9Y5N1 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
CHRM2 P08172 2/20 0.31
CHRM4 P08173 2/20 0.31
CHRM5 P08912 2/20 0.31
CHRM1 P11229 2/20 0.31
CHRM3 P20309 2/20 0.31
MGLL Q99685 2/20 0.31
PTPN1 P18031 1/20 0.31
MGAM O43451 1/20 0.30
APOBEC3A P31941 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9721065 0.78 TDP1 (0.42) ALDH1A1GLATDP1KMT2AMEN1
SCHEMBL11290142 0.76 TSHR (0.46) ALDH1A1GLATDP1KMT2AMEN1
SCHEMBL2018047 0.76 TSHR (0.46) ALDH1A1GLATDP1KMT2AMEN1
SCHEMBL5605973 0.75 ALDH1A1 (0.33) ALDH1A1TP53CYP3A4TSHRSMN1; SMN2
SCHEMBL10420263 0.75 ALDH1A1 (0.33) ALDH1A1TSHRSMN1; SMN2
SCHEMBL187736 0.75 ALDH1A1 (0.33) ALDH1A1TSHRSMN1; SMN2
SCHEMBL9560206 0.75 TSHR (0.49) ALDH1A1GLATDP1KMT2AMEN1
SCHEMBL5265710 0.75 TDP1 (0.45) ALDH1A1GLATDP1KMT2AMEN1
SCHEMBL203349 0.74 TDP1 (0.42) ALDH1A1GLATDP1KMT2AMEN1
SCHEMBL5832163 0.73 SMN1; SMN2 (0.33) ALDH1A1SMN1; SMN2CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4786667-A HEAT AND WEATHER RESISTANCE, SEALANT TOSHIBA SILICONE CO., LTD. (JP) 1988-11-22 US disclosed