Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.46 |
| ▸ | PTPRF | P10586 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 2/20 | 0.46 |
| ▸ | PTPRB | P23467 | 2/20 | 0.46 |
| ▸ | PTPRE | P23469 | 2/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20877511 | 0.85 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30955844 | 0.85 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL23136480 | 0.83 | GPR35 (0.53) | GPR35PTPN2PTPRFPTPRCPTPRB | |
| SCHEMBL27664630 | 0.80 | SNCA (0.57) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5697299 | 0.80 | GPR35 (0.68) | GPR35PTPN2PTPRFPTPRCPTPRB | |
| SCHEMBL172214 | 0.79 | CYP2C19 (0.65) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11883844 | 0.79 | TGM2 (0.55) | PTPN1PTPN11CYP1A2CYP3A4CYP2D6 | |
| Ethylene SCHEMBL7111690 | 0.76 | CYP2C19 (0.61) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28808749 | 0.76 | CYP2C19 (0.52) | CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL9779568 | 0.75 | ALDH1A1 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198452-A | Leukotriene antagonist, lipoxygenase or cyclooxygenase inhibitors, antihistamines or antiallergens | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| EP-0466125-A2 | Styryl compounds and their pharmaceutical use | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |