Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560896 | 1.00 | MAPK14 (0.39) | MAPK14MRGPRX4LTA4HEPHX2LPAR1 | |
| SCHEMBL9560573 | 0.89 | L3MBTL1 (0.38) | MRGPRX4LPAR1LPAR5SRD5A2 | |
| SCHEMBL9560570 | 0.89 | L3MBTL1 (0.38) | MRGPRX4LPAR1LPAR5SRD5A2 | |
| SCHEMBL9561164 | 0.87 | LPAR1 (0.36) | LPAR1LPAR5 | |
| SCHEMBL9560802 | 0.87 | RAB9A (0.38) | MAPK14EPHX2LPAR1LPAR5RXRA | |
| SCHEMBL9561171 | 0.87 | LPAR1 (0.36) | LPAR1LPAR5 | |
| SCHEMBL9560799 | 0.87 | RAB9A (0.38) | MAPK14EPHX2LPAR1LPAR5RXRA | |
| SCHEMBL9560817 | 0.85 | MAPK14 (0.52) | MAPK14MRGPRX4LTA4HEPHX2CETP | |
| SCHEMBL9560811 | 0.85 | MAPK14 (0.52) | MAPK14MRGPRX4LTA4HEPHX2CETP | |
| SCHEMBL9804279 | 0.83 | LTA4H (0.40) | MAPK14LTA4HEPHX2LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |