Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | IDH1 | O75874 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10453384 | 0.81 | MEN1 (0.43) | BCL2BCL2L1ALOX5MEN1CYP3A4 | |
| SCHEMBL10359608 | 0.81 | TRPA1 (0.46) | BCL2BCL2L1TSHRALOX5MEN1 | |
| SCHEMBL10454618 | 0.81 | TP53 (0.46) | BCL2BCL2L1ALOX5MEN1CYP3A4 | |
| SCHEMBL28182676 | 0.80 | CYP4F2 (0.47) | TSHRMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL11890536 | 0.79 | ALOX15 (0.62) | BCL2BCL2L1TSHRALOX5MEN1 | |
| SCHEMBL27691632 | 0.79 | HTR2A (0.42) | BCL2BCL2L1ALOX5MEN1CYP3A4 | |
| SCHEMBL16192444 | 0.79 | BCL2 (0.47) | BCL2BCL2L1ALOX5MEN1CYP3A4 | |
| SCHEMBL10454613 | 0.77 | FFAR1 (0.41) | BCL2BCL2L1ALOX5MEN1CYP3A4 | |
| SCHEMBL10547587 | 0.77 | BCL2 (0.39) | BCL2BCL2L1TSHRALOX5MEN1 | |
| SCHEMBL10642063 | 0.77 | ALOX5 (0.42) | BCL2BCL2L1ALOX5MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253536-A2 | Fluorobenzyl esters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-20 | — | — | EP | claimed |
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| CN-1019191-B | INSECTICIDAL ETHERS | ICI PLC (GB) | 1992-11-25 | — | — | CN | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| CN-1014061-B | The preparation method of pyrimidine derivatives | ICI PLC (GB) | 1991-09-25 | — | — | CN | disclosed |
| EP-0227369-B1 | INSECTICIDAL ALKENES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-04-18 | — | — | EP | disclosed |
| US-4904677-A | Certain phenoxy- or benzyl substituted pyridylmethyloxy-alkenes having insecticidal properties | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-27 | — | — | US | disclosed |
| US-4902814-A | CHEMICAL INTERMEDIATES FOR INSECTICIDES AND ACARICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-20 | — | — | US | disclosed |
| US-4812483-A | PESTICIDES, MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-03-14 | — | — | US | disclosed |
| US-4762835-A | INSECTICIDES, MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-09 | — | — | US | disclosed |
| CN-87105021-A | FLUOROBENZYL ESTERS | — | 1988-01-27 | — | — | CN | disclosed |
| EP-0253536-A2 | Fluorobenzyl esters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-20 | — | — | EP | disclosed |
| EP-0253536-A2 | Fluorobenzyl esters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-20 | — | — | EP | disclosed |
| CN-86108786-A | INSECTICIDAL ALKENES | — | 1987-07-22 | — | — | CN | disclosed |
| CN-86108825-A | PYRIMIDINE DERIVATIVES | — | 1987-07-22 | — | — | CN | disclosed |
| EP-0227415-A2 | Pyrimidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-01 | — | — | EP | disclosed |
| EP-0227369-A1 | Insecticidal alkenes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-01 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |
| CN-86105891-A | Desinsection ether | — | 1987-02-25 | — | — | CN | disclosed |