Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 4/20 | 0.37 |
| ▸ | MARS1 | P56192 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.30 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561744 | 0.85 | PRMT5 (0.39) | ADCY5MARS1PRMT5CARM1PRMT1 | |
| SCHEMBL9561486 | 0.85 | PRMT5 (0.39) | ADCY5MARS1PRMT5CARM1PRMT1 | |
| SCHEMBL9561462 | 0.83 | CPB1 (0.40) | ADCY5PRMT5CARM1PRMT1WDR77 | |
| SCHEMBL9561069 | 0.83 | CPB1 (0.40) | ADCY5PRMT5CARM1PRMT1WDR77 | |
| SCHEMBL10534213 | 0.73 | NPY4R (0.36) | PRMT5CARM1PRMT1WDR77PRMT7 | |
| SCHEMBL10532237 | 0.71 | ADCY5 (0.46) | ADCY5ADORA2AFGFR1SLC22A6ADCY1 | |
| SCHEMBL9561473 | 0.71 | HPRT1 (0.41) | PRMT5CARM1PRMT1WDR77PRMT7 | |
| SCHEMBL9561734 | 0.71 | HPRT1 (0.41) | PRMT5CARM1PRMT1WDR77PRMT7 | |
| Hydrochloric Acid SCHEMBL9561683 | 0.71 | ADCY5 (0.45) | ADCY5ADORA2AFGFR1SLC22A6ADCY1 | |
| SCHEMBL9561494 | 0.70 | ADCY5 (0.40) | ADCY5ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346460-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION. | CO PHARMA CORP SRL (IT) | 1989-12-20 | — | — | EP | claimed |
| WO-1989005818-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION S.R.L. (IT) | 1989-06-29 | — | — | WO | claimed |