Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637914 | 1.00 | NQO1 (0.47) | NQO1TDP1TSHRPDK2LMNA | |
| SCHEMBL9861827 | 0.77 | SLC6A4 (0.44) | MAPT | |
| SCHEMBL9560429 | 0.77 | KDM1A (0.43) | PDK2SLC5A2L3MBTL1SLC5A1CYP1A2 | |
| SCHEMBL9561216 | 0.74 | MAOB (0.39) | TDP1L3MBTL1ATM | |
| SCHEMBL9561359 | 0.74 | CYP1A2 (0.31) | CYP1A2 | |
| SCHEMBL2173955 | 0.72 | SLC6A3 (0.38) | — | |
| SCHEMBL28395980 | 0.71 | NQO1 (0.48) | NQO1TDP1TSHRPDK2LMNA | |
| SCHEMBL9560864 | 0.71 | TAAR1 (0.36) | — | |
| SCHEMBL9560749 | 0.71 | MAOA (0.39) | PDK2LMNA | |
| SCHEMBL20087810 | 0.70 | MAOB (0.38) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3047176-A | — | — | None | — | — | JP | disclosed |
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0276558-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-08 | — | — | EP | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0273549-B1 | INSECTICIDAL THIOETHERS AND DERIVATIVES THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-02 | — | — | EP | disclosed |
| US-5068461-A | 1,1,1-trifluoro-2-(4-alkoxyphenyl)prop-2-ene compounds for aphids, mites and other insects | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-26 | — | — | US | disclosed |
| JP-H0347176-A | NOVEL COMPOUND | IMPERIAL CHEM IND PLC <ICI> | 1991-02-28 | — | — | JP | disclosed |
| US-4937388-A | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-26 | — | — | US | disclosed |
| EP-0276558-A2 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-03 | — | — | EP | disclosed |
| EP-0273549-A1 | Insecticidal thioethers and derivatives thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-06 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |