Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4982095 | 0.81 | SLC6A4 (0.45) | SLC6A4SLC6A3SLC6A2PIM1PIM2 | |
| SCHEMBL9561250 | 0.77 | NQO1 (0.47) | MAPT | |
| SCHEMBL9637914 | 0.77 | NQO1 (0.47) | MAPT | |
| SCHEMBL2173955 | 0.76 | SLC6A3 (0.38) | SLC6A4SLC6A3SLC6A2NR1I2 | |
| SCHEMBL9561216 | 0.75 | MAOB (0.39) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL9560749 | 0.75 | MAOA (0.39) | SLC6A4SLC6A3SLC6A2KDM1A | |
| SCHEMBL9560864 | 0.75 | TAAR1 (0.36) | — | |
| SCHEMBL20087810 | 0.74 | MAOB (0.38) | SLC6A3SLC6A2 | |
| SCHEMBL254957 | 0.72 | MAPT (0.56) | PIM1PIM2MAPTEPHX2NISCH | |
| SCHEMBL9560600 | 0.72 | NPC1 (0.40) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068461-A | 1,1,1-trifluoro-2-(4-alkoxyphenyl)prop-2-ene compounds for aphids, mites and other insects | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-26 | — | — | US | disclosed |
| US-4937388-A | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-26 | — | — | US | disclosed |
| EP-0273549-A1 | Insecticidal thioethers and derivatives thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-06 | — | — | EP | disclosed |