Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12762780 | 0.95 | TDP1 (0.63) | TDP1HSD17B10USP2HTT | |
| SCHEMBL135405 | 0.95 | TDP1 (0.68) | TDP1HSD17B10USP2HTTSPHK1 | |
| Ammonia Solution, Strong SCHEMBL29094792 | 0.92 | TDP1 (0.65) | TDP1HSD17B10USP2HTT | |
| SCHEMBL26241019 | 0.91 | TDP1 (0.53) | TDP1HSD17B10USP2 | |
| SCHEMBL1478603 | 0.91 | TDP1 (0.64) | TDP1HSD17B10USP2 | |
| SCHEMBL1478045 | 0.90 | TDP1 (0.69) | TDP1HSD17B10USP2HTT | |
| SCHEMBL4595090 | 0.90 | TDP1 (0.63) | TDP1HSD17B10USP2HTT | |
| SCHEMBL437182 | 0.90 | TDP1 (0.69) | TDP1HSD17B10USP2HTT | |
| SCHEMBL28728852 | 0.90 | TDP1 (0.69) | TDP1HSD17B10USP2HTT | |
| SCHEMBL27954020 | 0.90 | TDP1 (0.69) | TDP1HSD17B10USP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2017-01-12 | — | — | US | disclosed |
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2017-01-12 | — | — | US | disclosed |
| US-9499579-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2016-11-22 | — | — | US | disclosed |
| US-8546534-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO. INC. (JP) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, BCAT2, IAPP | TDP1 4323/4885HSD17B10 420/4885USP2 3271/4885 |
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, IAPP, BCAT1 | TDP1 4224/4885HSD17B10 664/4885USP2 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.