Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561496 | 1.00 | ALOX5 (0.33) | ALOX5L3MBTL1LMNAMAPTATM | |
| SCHEMBL9560512 | 0.91 | LMNA (0.40) | ALOX5L3MBTL1LMNAMAPTATM | |
| SCHEMBL9561335 | 0.88 | CETP (0.41) | FFAR1CETP | |
| SCHEMBL9561343 | 0.88 | CETP (0.41) | FFAR1CETP | |
| SCHEMBL9637902 | 0.86 | L3MBTL1 (0.33) | ALOX5L3MBTL1LMNAMAPTATM | |
| SCHEMBL9637906 | 0.86 | L3MBTL1 (0.33) | ALOX5L3MBTL1LMNAMAPTATM | |
| SCHEMBL9560338 | 0.86 | ALOX5 (0.33) | ALOX5PPARGPSEN1TACR1FFAR1 | |
| SCHEMBL9560793 | 0.86 | NR4A1 (0.36) | TACR1LPAR1LPAR5CETPTTR | |
| SCHEMBL9560403 | 0.86 | NR3C2 (0.37) | ALOX5L3MBTL1LMNALPAR1LPAR5 | |
| SCHEMBL9560585 | 0.86 | MAPK14 (0.39) | ALOX5PPARGPSEN1TACR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| EP-0276558-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-08 | — | — | EP | disclosed |
| EP-0276558-A2 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-03 | — | — | EP | disclosed |