SCHEMBL9561689

SCHEMBL9561689

CC(C(=O)c1ccccc1)C12CCCN1CCC2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.42
SLC6A3 Q01959 1/20 0.42
PGR P06401 1/20 0.41
ADRA2A P08913 1/20 0.41
ADRA2B P18089 1/20 0.41
HTR2A P28223 1/20 0.41
HRH1 P35367 1/20 0.41
KCNH2 Q12809 1/20 0.41
ALDH1A1 P00352 6/20 0.40
LMNA P02545 2/20 0.40
TSHR P16473 2/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTT P42858 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
MITF O75030 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6433697 0.72 SLC6A2 (0.43) SLC6A2SLC6A3PGRADRA2AADRA2B
SCHEMBL10372706 0.70 ATM (0.57) KCNH2ALDH1A1LMNATSHRCYP3A4
SCHEMBL9561706 0.68 ALDH1A1 (0.51) SLC6A2SLC6A3KCNH2ALDH1A1LMNA
SCHEMBL11037118 0.68 SLC6A2 (0.67) SLC6A2SLC6A3ALDH1A1LMNATSHR
SCHEMBL28360223 0.68 SLC6A2 (0.67) SLC6A2SLC6A3ALDH1A1LMNATSHR
SCHEMBL96304 0.67 TDP1 (0.54) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL1072701 0.67 SLC6A2 (0.69) SLC6A2SLC6A3ALDH1A1LMNATSHR
Hydrochloric Acid SCHEMBL22614730 0.67 SLC6A2 (0.65) SLC6A2SLC6A3ALDH1A1LMNATSHR
Hydrochloric Acid SCHEMBL28057449 0.67 SLC6A2 (0.65) SLC6A2SLC6A3ALDH1A1LMNATSHR
Hydrochloric Acid SCHEMBL10728832 0.66 SLC6A2 (0.68) SLC6A2SLC6A3ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0558321-A1 Antivirally active N-cycloalkyl alkanol compounds SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1993-09-01 EP disclosed