Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.69 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.69 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.69 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.69 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.69 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.69 |
| ▸ | CHRNG | P07510 | 4/20 | 0.69 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.69 |
| ▸ | CHRND | Q07001 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10728832 | 0.98 | SLC6A2 (0.68) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| Bromide SCHEMBL13729160 | 0.98 | SLC6A2 (0.68) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL28360223 | 0.98 | SLC6A2 (0.67) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL11037118 | 0.98 | SLC6A2 (0.67) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| Hydrochloric Acid SCHEMBL22614730 | 0.96 | SLC6A2 (0.65) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| Hydrochloric Acid SCHEMBL28057449 | 0.96 | SLC6A2 (0.65) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL6811754 | 0.84 | ALDH1A1 (0.61) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL1714913 | 0.83 | SLC6A2 (0.50) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL4869220 | 0.83 | OPRD1 (0.53) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL9360364 | 0.83 | SLC6A3 (0.60) | SLC6A2SLC6A3CHRNB4CHRNA3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486831-A | Preparation method of phenyllansoprazole impurity 1, 5-diphenyl-2- (piperidine-1-methyl) -1, 5-pentanedione hydrochloride | 湖南中南制药有限责任公司 | 2024-02-02 | — | — | CN | claimed |
| JP-56043266-A | — | — | None | — | — | JP | disclosed |
| JP-58216156-A | — | — | None | — | — | JP | disclosed |
| CN-117486831-A | Preparation method of phenyllansoprazole impurity 1, 5-diphenyl-2- (piperidine-1-methyl) -1, 5-pentanedione hydrochloride | 湖南中南制药有限责任公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117486831-A | Preparation method of phenyllansoprazole impurity 1, 5-diphenyl-2- (piperidine-1-methyl) -1, 5-pentanedione hydrochloride | 湖南中南制药有限责任公司 | 2024-02-02 | — | — | CN | disclosed |
| EP-2271645-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009126514-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2009-10-15 | — | — | WO | disclosed |
| EP-1383752-A2 | DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS | Turicum Drug Development AG (CH) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002088100-A2 | DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS | TURICUM DRUG DEVELOPMENT AG (CH) | 2002-11-07 | — | — | WO | disclosed |
| JP-S58216156-A | PRODUCTION OF PIPERIDINOPROPANOL DERIVATIVE | IWAKI SEIYAKU KK | 1983-12-15 | — | — | JP | disclosed |
| US-4361573-A | α,α-Diaryl-β-(tert-amino)-propanols and diuretic pharmaceutical compositions containing them | TEMMLER AG (CH) | 1982-11-30 | — | — | US | disclosed |
| JP-S5643266-A | PRODUCTION OF PIPERIDINOPROPANOL DERIVATIVE | IWAKI SEIYAKU KK | 1981-04-21 | — | — | JP | disclosed |
| US-4025633-A | DIURETICS, SALURETICS | FIRMA TEMMLER A.G. (CH) | 1977-05-24 | — | — | US | disclosed |