Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495842 | 0.89 | HRH3 (0.46) | HRH3SLC6A4GBA1TACR1 | |
| Hydrochloric Acid SCHEMBL7982684 | 0.88 | HRH3 (0.45) | HRH3SLC6A4TACR1 | |
| SCHEMBL9562200 | 0.83 | MAOA (0.57) | GBA1MAOAMAOB | |
| SCHEMBL8307801 | 0.81 | MAOB (0.53) | HRH3SLC6A4GBA1TACR1MAOB | |
| SCHEMBL16138420 | 0.81 | GBA1 (0.55) | HRH3SLC6A4GBA1 | |
| Hydrochloric Acid SCHEMBL16112905 | 0.79 | GBA1 (0.53) | HRH3SLC6A4GBA1 | |
| SCHEMBL8430018 | 0.76 | MAOB (0.38) | MAOAMAOB | |
| SCHEMBL20015572 | 0.76 | MAOB (0.48) | SLC6A4TACR1MAOB | |
| SCHEMBL22265774 | 0.74 | HRH4 (0.44) | HRH3SLC6A4GBA1 | |
| SCHEMBL29889588 | 0.74 | HRH4 (0.44) | HRH3SLC6A4GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1069491-A | 2-(piperidines-1-yl) alcohol derivative, its method for making and treatment thereof are used | SYNTHELABO (FR) | 1993-03-03 | — | — | CN | disclosed |
| EP-0524846-A1 | 2-(Piperidin-1-yl)ethanol derivatives, their preparation and their use in therapeutics | SYNTHELABO (FR) | 1993-01-27 | — | — | EP | disclosed |