Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561544 | 0.85 | POLB (0.51) | KMT2APOLBMEN1ITGB3ITGA2B | |
| SCHEMBL9561714 | 0.84 | ALDH1A1 (0.50) | KMT2APOLBKDM4EALDH1A1RECQL | |
| SCHEMBL9561712 | 0.81 | HPGD (0.48) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL9561715 | 0.79 | HPGD (0.46) | KMT2AMEN1KDM4EALDH1A1KDM5A | |
| SCHEMBL8945334 | 0.74 | POLB (0.54) | KMT2APOLBMEN1ITGB3ITGA2B | |
| SCHEMBL15994317 | 0.71 | JMJD7 (0.49) | KMT2APOLBMEN1KDM4EALDH1A1 | |
| Safironil SCHEMBL344153 | 0.70 | ALDH1A1 (0.62) | KMT2AMEN1ITGB3ITGA2BKDM4E | |
| SCHEMBL5214396 | 0.70 | KDM5B (0.60) | POLBKDM4EKDM5AKDM5CKDM5B | |
| SCHEMBL14904964 | 0.69 | KMT2A (0.52) | KMT2APOLBMEN1SMN1; SMN2 | |
| SCHEMBL8945406 | 0.69 | ALDH1A1 (0.59) | KMT2AKDM4EALDH1A1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260323-A | 2,4- and 2,5-substituted pyridine-N-oxides, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |