Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | THRA | P10827 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561846 | 1.00 | THRB (0.36) | THRBPRSS1PRSS2PRSS3MAPT | |
| SCHEMBL9562079 | 0.89 | ALDH1A1 (0.41) | PRSS1PRSS2PRSS3MAPTALDH1A1 | |
| SCHEMBL9561548 | 0.87 | PRSS1 (0.38) | THRBPRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL9346741 | 0.83 | THRB (0.48) | THRBMAPTTHRACNR1CNR2 | |
| SCHEMBL9346722 | 0.83 | THRB (0.48) | THRBMAPTTHRACNR1CNR2 | |
| SCHEMBL9562081 | 0.80 | THRB (0.43) | THRBMAPTTHRAPPARGS1PR3 | |
| SCHEMBL9341888 | 0.77 | KDM4E (0.42) | MAPTALDH1A1LMNACYP3A4CYP2C9 | |
| SCHEMBL9561526 | 0.76 | THRB (0.33) | THRBPRSS1PRSS2PRSS3PPARG | |
| SCHEMBL17712582 | 0.76 | CNR1 (0.43) | THRBMAPTTHRACNR1CNR2 | |
| SCHEMBL8375387 | 0.73 | KMT2A (0.53) | PRSS1PRSS2PRSS3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5232624-A | Components of tilted smectic liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-08-03 | — | — | US | disclosed |