Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768325 | 0.82 | KCNH2 (0.61) | KCNH2GRIN2BKDM4EHTR1ADRD2 | |
| SCHEMBL9562529 | 0.79 | KCNH2 (0.57) | KCNH2GRIN2BHTR2ATSHRGMNN | |
| SCHEMBL9562326 | 0.79 | KCNH2 (0.56) | KCNH2GRIN2BKDM4EHTR1ADRD2 | |
| SCHEMBL9561898 | 0.77 | KCNH2 (0.55) | KCNH2GRIN2BHTR1ADRD2HTR2A | |
| SCHEMBL9562497 | 0.76 | KCNH2 (0.57) | KCNH2GRIN2BHTR1ADRD2HTR2A | |
| SCHEMBL10722357 | 0.76 | KDM4E (0.49) | GRIN2BKDM4ETSHRGMNNTP53 | |
| SCHEMBL10726153 | 0.75 | KDM4E (0.39) | GRIN2BKDM4EALDH1A1TSHRGMNN | |
| SCHEMBL8439768 | 0.75 | KCNH2 (0.54) | KCNH2GRIN2BHTR1ADRD2HTR2A | |
| SCHEMBL10724902 | 0.74 | CCR3 (0.41) | KCNH2GRIN2BKDM4EHTR1ADRD2 | |
| SCHEMBL8301971 | 0.74 | KCNH2 (0.52) | KCNH2GRIN2BHTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524846-A1 | 2-(Piperidin-1-yl)ethanol derivatives, their preparation and their use in therapeutics | SYNTHELABO (FR) | 1993-01-27 | — | — | EP | disclosed |