Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | OGT | O15294 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466863 | 0.81 | GRIN2B (0.61) | KCNH2GRIN2BALDH1A1ATMHTR1A | |
| SCHEMBL9561851 | 0.80 | GRIN2B (0.56) | KCNH2GRIN2BALDH1A1ATMHTR1A | |
| SCHEMBL9562478 | 0.79 | GRIN2B (0.60) | KCNH2GRIN2BALDH1A1ATMHTR1A | |
| Hydrochloric Acid SCHEMBL8542941 | 0.78 | MEN1 (0.56) | KCNH2GRIN2BALDH1A1ATMOGT | |
| SCHEMBL9562306 | 0.77 | KCNH2 (0.57) | KCNH2GRIN2BALDH1A1ATMHTR1A | |
| SCHEMBL8439768 | 0.77 | KCNH2 (0.54) | KCNH2GRIN2BALDH1A1ATMHTR1A | |
| SCHEMBL8301971 | 0.76 | KCNH2 (0.52) | KCNH2GRIN2BALDH1A1ATMHTR1A | |
| SCHEMBL8549343 | 0.74 | GRIN2B (0.59) | GRIN2BOGTMEN1KMT2A | |
| SCHEMBL5467351 | 0.74 | KCNH2 (0.55) | KCNH2GRIN2BALDH1A1ATMHTR1A | |
| SCHEMBL9562529 | 0.74 | KCNH2 (0.57) | KCNH2GRIN2BHTR2ABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524846-A1 | 2-(Piperidin-1-yl)ethanol derivatives, their preparation and their use in therapeutics | SYNTHELABO (FR) | 1993-01-27 | — | — | EP | disclosed |