Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562497 | 0.93 | KCNH2 (0.57) | KCNH2GRIN2BGMNNTP53CYP3A4 | |
| SCHEMBL9561877 | 0.92 | KCNH2 (0.52) | KCNH2GRIN2BTSHRACHEMAOB | |
| SCHEMBL9562489 | 0.91 | KCNH2 (0.51) | KCNH2GRIN2BGMNNTP53CYP3A4 | |
| SCHEMBL466863 | 0.91 | GRIN2B (0.61) | KCNH2GRIN2BACHEMAOBHTR2A | |
| SCHEMBL9562383 | 0.86 | GMNN (0.44) | KCNH2GRIN2BGMNNTP53CYP3A4 | |
| SCHEMBL9562478 | 0.85 | GRIN2B (0.60) | KCNH2GRIN2BSLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9768325 | 0.85 | KCNH2 (0.61) | KCNH2GRIN2BGMNNTP53CYP3A4 | |
| SCHEMBL9562326 | 0.84 | KCNH2 (0.56) | KCNH2GRIN2BGMNNTP53CYP3A4 | |
| SCHEMBL8439768 | 0.83 | KCNH2 (0.54) | KCNH2GRIN2BTSHRHTR2A | |
| SCHEMBL9768368 | 0.82 | GRIN2B (0.60) | KCNH2GRIN2BGMNNTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524846-A1 | 2-(Piperidin-1-yl)ethanol derivatives, their preparation and their use in therapeutics | SYNTHELABO (FR) | 1993-01-27 | — | — | EP | disclosed |