Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562302 | 0.92 | PTPRC (0.55) | PTPRCESR1ESR2PTGS2BACE1 | |
| SCHEMBL9562267 | 0.92 | PTPRC (0.55) | PTPRCESR1ESR2PTGS2BACE1 | |
| SCHEMBL9562297 | 0.85 | PTPRC (0.59) | PTPRCESR1ESR2PTGS2BACE1 | |
| SCHEMBL9561882 | 0.84 | PTPRC (0.65) | PTPRCESR1ESR2PTGS2BACE1 | |
| SCHEMBL9561883 | 0.82 | HKDC1 (0.52) | PTPRCBACE1MAPTNSD2OPRM1 | |
| SCHEMBL9562523 | 0.78 | PTPRC (0.80) | PTPRCESR1ESR2PTGS2BACE1 | |
| SCHEMBL6232476 | 0.76 | PTPRC (1.00) | PTPRCESR1ESR2PTGS2BACE1 | |
| SCHEMBL7716516 | 0.71 | PTPRC (0.64) | PTPRCESR1ESR2PTGS2MAPT | |
| SCHEMBL10881204 | 0.71 | BACE1 (0.68) | PTPRCBACE1MAPTNSD2OPRM1 | |
| SCHEMBL7231941 | 0.70 | ESR1 (0.62) | PTPRCESR1ESR2PTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560684-A1 | 1,4-naphthoquinone or 1,4-naphthalenediol compounds di- or tri-indolyl substituted, processes for their preparation and their use for dyeing keratinous material | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560684-A1 | 1,4-naphthoquinone or 1,4-naphthalenediol compounds di- or tri-indolyl substituted, processes for their preparation and their use for dyeing keratinous material | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |