Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | PTPRC | P08575 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562302 | 0.91 | PTPRC (0.55) | HKDC1CCR6PTPRCBACE1 | |
| SCHEMBL9562267 | 0.91 | PTPRC (0.55) | HKDC1CCR6PTPRCNSD2OPRM1 | |
| SCHEMBL9562546 | 0.85 | BACE1 (0.57) | HKDC1CCR6PTPRCNSD2OPRM1 | |
| SCHEMBL9572012 | 0.85 | BACE1 (0.57) | HKDC1CCR6PTPRCNSD2OPRM1 | |
| SCHEMBL9562325 | 0.82 | PTPRC (0.60) | HKDC1PTPRCNSD2OPRM1OPRD1 | |
| SCHEMBL9562286 | 0.79 | CCR6 (0.62) | HKDC1CCR6PTPRCMEN1MAPT | |
| SCHEMBL8992318 | 0.76 | PTPRC (0.70) | HKDC1CCR6PTPRCNSD2OPRM1 | |
| SCHEMBL7716546 | 0.72 | CCR6 (0.53) | HKDC1CCR6PTPRCNSD2MEN1 | |
| SCHEMBL9561882 | 0.71 | PTPRC (0.65) | HKDC1PTPRCNSD2OPRM1OPRD1 | |
| SCHEMBL9572019 | 0.70 | PTPN1 (0.59) | HKDC1PTPRCNSD2OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560684-A1 | 1,4-naphthoquinone or 1,4-naphthalenediol compounds di- or tri-indolyl substituted, processes for their preparation and their use for dyeing keratinous material | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560684-A1 | 1,4-naphthoquinone or 1,4-naphthalenediol compounds di- or tri-indolyl substituted, processes for their preparation and their use for dyeing keratinous material | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |