Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.55 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.43 |
| ▸ | ESR1 | P03372 | 4/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | DDX3X | O00571 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562267 | 0.96 | PTPRC (0.55) | PTPRCCCR6HKDC1PTGS2ESR1 | |
| SCHEMBL9562325 | 0.92 | PTPRC (0.60) | PTPRCHKDC1PTGS2ESR1ESR2 | |
| SCHEMBL9561883 | 0.91 | HKDC1 (0.52) | PTPRCCCR6HKDC1BACE1 | |
| SCHEMBL9561882 | 0.80 | PTPRC (0.65) | PTPRCHKDC1PTGS2ESR1ESR2 | |
| SCHEMBL9562297 | 0.78 | PTPRC (0.59) | PTPRCPTGS2ESR1ESR2BACE1 | |
| SCHEMBL9562546 | 0.77 | BACE1 (0.57) | PTPRCCCR6HKDC1BACE1 | |
| SCHEMBL9572012 | 0.77 | BACE1 (0.57) | PTPRCCCR6HKDC1BACE1 | |
| SCHEMBL9562523 | 0.74 | PTPRC (0.80) | PTPRCCCR6HKDC1PTGS2ESR1 | |
| SCHEMBL6252574 | 0.73 | PTGS2 (0.53) | PTPRCCCR6HKDC1PTGS2ESR1 | |
| SCHEMBL9562597 | 0.71 | PTPRC (0.59) | PTPRCCCR6HKDC1PTGS2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560684-A1 | 1,4-naphthoquinone or 1,4-naphthalenediol compounds di- or tri-indolyl substituted, processes for their preparation and their use for dyeing keratinous material | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560684-A1 | 1,4-naphthoquinone or 1,4-naphthalenediol compounds di- or tri-indolyl substituted, processes for their preparation and their use for dyeing keratinous material | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |