Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475988 | 0.84 | NPC1 (0.54) | KMT2ANPC1MAPTTHRBLMNA | |
| SCHEMBL10418697 | 0.80 | BCL9 (0.40) | KMT2ANPC1MAPTTHRBHPGD | |
| SCHEMBL9406188 | 0.80 | PRSS1 (0.47) | KMT2ACCNCCDK8NPC1MAPT | |
| SCHEMBL1994064 | 0.79 | ALOX15 (0.49) | KMT2AALOX15ALDH1A1LMNAMEN1 | |
| SCHEMBL14766407 | 0.79 | MAPT (0.48) | KMT2ACCNCCDK8NPC1MAPT | |
| SCHEMBL14767194 | 0.79 | MAPT (0.48) | KMT2ACCNCCDK8NPC1MAPT | |
| SCHEMBL10418081 | 0.79 | KMT2A (0.46) | KMT2ACCNCCDK8NPC1MAPT | |
| SCHEMBL20703605 | 0.77 | BCL9 (0.60) | KMT2ANPC1MAPTPARP10L3MBTL1 | |
| SCHEMBL9405801 | 0.77 | NPC1 (0.59) | KMT2ANPC1MAPTLMNA | |
| SCHEMBL10381844 | 0.77 | MAPT (0.47) | KMT2ANPC1MAPTTHRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248447-A | 2,3-difluorohydroquinone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-28 | — | — | US | disclosed |
| EP-0518961-A1 | DERIVATIVES OF GLYCINAMIDE, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Aventis Pharma S.A. (FR) | 1992-12-23 | — | — | EP | disclosed |