SCHEMBL9562382

SCHEMBL9562382

CC(=O)Nc1ccc(CCC2CCNCC2)cc1

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 1/20 0.46
AOC3 Q16853 1/20 0.45
ITGB3 P05106 1/20 0.44
ITGA2B P08514 1/20 0.44
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6162059 0.85 GBA1 (0.51) NAMPTKDM4EALDH1A1
SCHEMBL9236549 0.80 KMT2A (0.54) NAMPTITGB3ITGA2BKDM4E
Bicarbonate SCHEMBL9236556 0.79 PTPN1 (0.52)
Hydrochloric Acid SCHEMBL9238478 0.78 ITGB3 (0.52) ITGB3ITGA2BALDH1A1
SCHEMBL28051643 0.78
Hydrochloric Acid SCHEMBL9234702 0.77 S1PR1 (0.54) ITGB3ITGA2B
Hydrochloric Acid SCHEMBL9234472 0.77 PRMT3 (0.45)
SCHEMBL19186859 0.77 CNR2 (0.48) NAMPTAOC3KDM4EALDH1A1
SCHEMBL27670154 0.77 CYP4A11 (0.51) ITGB3ITGA2BALDH1A1
SCHEMBL14621350 0.77 ITGB3 (0.47) ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1106400-A Heteroarylpiperidines, process for their preparation and pharmaceutical compositions in which they are present SANOFI SA (FR) 1995-08-09 CN disclosed
CN-1069491-A 2-(piperidines-1-yl) alcohol derivative, its method for making and treatment thereof are used SYNTHELABO (FR) 1993-03-03 CN disclosed
EP-0524846-A1 2-(Piperidin-1-yl)ethanol derivatives, their preparation and their use in therapeutics SYNTHELABO (FR) 1993-01-27 EP disclosed