Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562508 | 0.93 | MEN1 (0.44) | GRIN2BKCNH2MAOBSLC6A3SLC6A2 | |
| SCHEMBL9562536 | 0.90 | KCNH2 (0.48) | GMNNTP53CYP3A4ALOX15TSHR | |
| SCHEMBL9562529 | 0.86 | KCNH2 (0.57) | GMNNTP53CYP3A4ALOX15TSHR | |
| SCHEMBL8521848 | 0.86 | KCNH2 (0.41) | GMNNTP53CYP3A4ALOX15TSHR | |
| SCHEMBL9562497 | 0.79 | KCNH2 (0.57) | GMNNTP53CYP3A4ALOX15TSHR | |
| SCHEMBL9561877 | 0.78 | KCNH2 (0.52) | TSHRGRIN2BKCNH2MAOBHTR2A | |
| SCHEMBL9562489 | 0.77 | KCNH2 (0.51) | GMNNTP53CYP3A4ALOX15TSHR | |
| SCHEMBL466863 | 0.77 | GRIN2B (0.61) | GRIN2BKCNH2MAOBHTR2A | |
| SCHEMBL9562581 | 0.76 | KCNH2 (0.38) | GRIN2BKCNH2 | |
| SCHEMBL9561894 | 0.74 | BCHE (0.50) | GRIN2BKCNH2MAOBSLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524846-A1 | 2-(Piperidin-1-yl)ethanol derivatives, their preparation and their use in therapeutics | SYNTHELABO (FR) | 1993-01-27 | — | — | EP | disclosed |