Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | OGT | O15294 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466863 | 0.84 | GRIN2B (0.61) | BCHEACHEGRIN2BMAOAMAOB | |
| SCHEMBL9562508 | 0.82 | MEN1 (0.44) | BCHEACHEGRIN2BMAOAMAOB | |
| SCHEMBL7305064 | 0.81 | CHRM2 (0.46) | BCHEACHEGRIN2BMAOAMAOB | |
| SCHEMBL9562529 | 0.79 | KCNH2 (0.57) | BCHEACHEGRIN2BMAOBKCNH2 | |
| SCHEMBL9562478 | 0.79 | GRIN2B (0.60) | BCHEACHEGRIN2BMAOAMAOB | |
| SCHEMBL9562497 | 0.77 | KCNH2 (0.57) | BCHEACHEGRIN2BKCNH2DRD2 | |
| SCHEMBL9561877 | 0.76 | KCNH2 (0.52) | BCHEACHEGRIN2BMAOBKCNH2 | |
| SCHEMBL9562489 | 0.75 | KCNH2 (0.51) | BCHEACHEGRIN2BMAOBKCNH2 | |
| SCHEMBL466903 | 0.75 | DRD2 (0.57) | BCHEACHEMAOAMAOBKCNH2 | |
| SCHEMBL9562383 | 0.74 | GMNN (0.44) | GRIN2BMAOBKCNH2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524846-A1 | 2-(Piperidin-1-yl)ethanol derivatives, their preparation and their use in therapeutics | SYNTHELABO (FR) | 1993-01-27 | — | — | EP | disclosed |