Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.50 |
| ▸ | KIF11 | P52732 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562529 | 0.92 | KCNH2 (0.57) | KCNH2GRIN2BMAOBBCHEACHE | |
| SCHEMBL9562489 | 0.90 | KCNH2 (0.51) | KCNH2GRIN2BMAOBBCHEACHE | |
| SCHEMBL466863 | 0.90 | GRIN2B (0.61) | KCNH2GRIN2BMAOBBCHEACHE | |
| SCHEMBL9562497 | 0.88 | KCNH2 (0.57) | KCNH2GRIN2BBCHEACHEHTR1A | |
| SCHEMBL9562478 | 0.84 | GRIN2B (0.60) | KCNH2GRIN2BMAOBBCHEACHE | |
| SCHEMBL8439768 | 0.82 | KCNH2 (0.54) | KCNH2GRIN2BHTR1ADRD2HTR2A | |
| SCHEMBL8301971 | 0.79 | KCNH2 (0.52) | KCNH2GRIN2BHTR1ADRD2HTR2A | |
| SCHEMBL9562383 | 0.78 | GMNN (0.44) | KCNH2GRIN2BMAOBHTR2ATSHR | |
| SCHEMBL9561894 | 0.76 | BCHE (0.50) | KCNH2GRIN2BMAOBBCHEACHE | |
| SCHEMBL9562326 | 0.76 | KCNH2 (0.56) | KCNH2GRIN2BHTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524846-A1 | 2-(Piperidin-1-yl)ethanol derivatives, their preparation and their use in therapeutics | SYNTHELABO (FR) | 1993-01-27 | — | — | EP | claimed |
| JP-5186460-A | — | — | None | — | — | JP | disclosed |
| US-5236887-A | HERBICIDAL HETEROCYCLIC SULFONYLUREA COMPOSITIONS SAFENED BY HERBICIDAL ACIDS SUCH AS 2,4-D BELOW A PH OF 5 | DOWELANCO (US) | 1993-08-17 | — | — | US | disclosed |
| JP-H05186460-A | 2-(1-PIPERIDYL)ETHANOL DERIVATIVE, ITS PREPARATION AND APPLICATION FOR THERAPY | SYNTHELABO SA | 1993-07-27 | — | — | JP | disclosed |
| EP-0524846-A1 | 2-(Piperidin-1-yl)ethanol derivatives, their preparation and their use in therapeutics | SYNTHELABO (FR) | 1993-01-27 | — | — | EP | disclosed |