Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 5/20 | 0.60 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
| ▸ | MTOR | P42345 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547611 | 0.91 | GRIN2B (0.61) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| SCHEMBL9562529 | 0.82 | KCNH2 (0.57) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| SCHEMBL8301786 | 0.82 | HTR1A (0.53) | GRIN2BGRIN1HTR1ADRD2HTR2A | |
| SCHEMBL8549047 | 0.81 | GRIN1 (0.63) | GRIN2BGRIN1MEN1KMT2AGRIN2D | |
| Hydrochloric Acid SCHEMBL8542941 | 0.79 | MEN1 (0.56) | GRIN2BGRIN1GMNNCYP3A4NFKB1 | |
| SCHEMBL4671945 | 0.79 | GRIN2B (0.58) | GRIN2BGRIN1HTR1ADRD2HTR2A | |
| SCHEMBL8548110 | 0.78 | GRIN2B (0.64) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8544786 | 0.78 | GRIN2B (0.59) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| SCHEMBL9562326 | 0.77 | KCNH2 (0.56) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| SCHEMBL9768325 | 0.77 | KCNH2 (0.61) | GRIN2BGRIN1GMNNTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2072173-A | — | — | None | — | — | JP | disclosed |
| US-5034401-A | Cardiovascular disorders or antiischemia agents | SYNTHELABO (FR) | 1991-07-23 | — | — | US | disclosed |
| JP-H0272173-A | HETEROCYCLIC COMPOUND, ITS PRODUCTION AND ITS APPLICATION TO MEDICINE | SYNTHELABO SA | 1990-03-12 | — | — | JP | disclosed |