SCHEMBL9563019

SCHEMBL9563019

COC(=O)C(Sc1nc(OC)cc(OC)n1)C1CCCSS1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
CYP1A2 P05177 1/20 0.33
ALOX5 P09917 4/20 0.32
PPARG P37231 3/20 0.32
KMT2A Q03164 1/20 0.32
PTGES O14684 2/20 0.31
PTGS2 P35354 1/20 0.31
PSEN1 P49768 1/20 0.31
KDM4E B2RXH2 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
TAS1R2 Q8TE23 1/20 0.31
ADORA3 P0DMS8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9562992 0.93 ALDH1A1 (0.34) ALDH1A1CYP1A2ALOX5PPARGPTGES
SCHEMBL9563044 0.90 ALOX5 (0.34) ALDH1A1ALOX5PPARGKMT2APTGES
SCHEMBL9563008 0.83 ALDH1A1 (0.35) ALDH1A1ALOX5PPARGPTGESPTGS2
SCHEMBL9563033 0.82 ALOX5 (0.36) ALDH1A1ALOX5PPARGPTGESPTGS2
SCHEMBL9562989 0.78 CYP1A2 (0.37) ALDH1A1CYP1A2ALOX5PPARGPTGES
SCHEMBL9563014 0.78 CYP1A2 (0.33) ALDH1A1CYP1A2ALOX5PPARGPTGES
SCHEMBL9562986 0.78 PTGES (0.40) ALDH1A1ALOX5PPARGPTGESPSEN1
SCHEMBL9563028 0.74 CYP1A2 (0.38) ALDH1A1CYP1A2KDM4EADORA3
SCHEMBL9563010 0.73 CYP1A2 (0.37) ALDH1A1CYP1A2KDM4EADORA3
SCHEMBL9368179 0.70 ALOX5 (0.43) ALDH1A1ALOX5PPARGPTGESPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0573837-A1 Acetal-containing pyrimidinylthioaliphatic acid derivatives useful as herbicides NIHON BAYER AGROCHEM K.K. (JP) 1993-12-15 EP disclosed