Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5835964 | 0.87 | KMT2A (0.50) | LMNAHPGDCYP2C19KMT2AALDH1A1 | |
| SCHEMBL9686671 | 0.84 | MMP8 (0.46) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL5836538 | 0.84 | LMNA (0.51) | LMNAHPGDCYP2C19SRCCYP2D6 | |
| SCHEMBL13898117 | 0.82 | LMNA (0.42) | LMNACYP2C19KMT2AMTNR1AMTNR1B | |
| SCHEMBL28026121 | 0.80 | KMT2A (0.55) | LMNACYP2C19KMT2AALDH1A1CYP3A4 | |
| SCHEMBL5836723 | 0.80 | KMT2A (0.55) | LMNACYP2C19KMT2AALDH1A1CYP3A4 | |
| SCHEMBL14419886 | 0.80 | LMNA (0.40) | LMNACYP2C19KMT2AAKT1ALDH1A1 | |
| SCHEMBL5836610 | 0.80 | MAPT (0.50) | LMNAKMT2ACES2CES1ALDH1A1 | |
| SCHEMBL9687500 | 0.78 | MMP8 (0.49) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL5835956 | 0.78 | KMT2A (0.51) | LMNACYP2C19SRCCYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557131-A2 | Polymer-supported catalysts | ROHM AND HAAS COMPANY (US) | 1993-08-25 | — | — | EP | claimed |
| EP-0557131-A2 | Polymer-supported catalysts | ROHM AND HAAS COMPANY (US) | 1993-08-25 | — | — | EP | disclosed |