Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687500 | 0.92 | MMP8 (0.49) | MMP8LMNAPIN1SMN1; SMN2MEN1 | |
| SCHEMBL7490890 | 0.90 | MMP8 (0.47) | MMP8LMNAPIN1SMN1; SMN2MEN1 | |
| SCHEMBL5835964 | 0.85 | KMT2A (0.50) | LMNAMEN1KMT2ATSHRSLC6A3 | |
| SCHEMBL9563164 | 0.84 | LMNA (0.53) | LMNASMN1; SMN2KMT2A | |
| SCHEMBL9796658 | 0.82 | MMP8 (0.48) | MMP8LMNAPIN1SMN1; SMN2MEN1 | |
| SCHEMBL27814580 | 0.80 | SMN1; SMN2 (0.59) | MMP8PIN1SMN1; SMN2TP53MEN1 | |
| SCHEMBL10869302 | 0.80 | MMP8 (0.51) | MMP8PIN1SMN1; SMN2TP53MEN1 | |
| SCHEMBL27419364 | 0.79 | MMP8 (0.46) | MMP8LMNAPIN1SMN1; SMN2MEN1 | |
| SCHEMBL3240811 | 0.78 | MMP8 (0.50) | MMP8LMNAPIN1SMN1; SMN2TP53 | |
| SCHEMBL11458679 | 0.78 | MMP8 (0.50) | MMP8LMNAPIN1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147952-A | PROCESS FOR PRODUCING MACROMOLECULAR MONOMER | TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-09-15 | — | — | US | disclosed |
| US-4596887-A | Cyclization of straight chain ketone, halogen containing derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-06-24 | — | — | US | disclosed |