Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533194 | 0.82 | FAAH (0.52) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL9563276 | 0.81 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL9563370 | 0.72 | SLC6A2 (0.50) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL9563175 | 0.72 | PARP14 (0.42) | TSHR | |
| SCHEMBL900325 | 0.71 | MLKL (0.40) | TSHR | |
| SCHEMBL12064964 | 0.68 | SLC6A2 (0.40) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL1802062 | 0.67 | DRD3 (0.59) | TSHRSLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL6999631 | 0.67 | TSHR (0.66) | TSHRSLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL8309087 | 0.67 | TSHR (1.00) | TSHRSLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL2476701 | 0.66 | MAPK1 (0.60) | TSHRSLC6A4SLC6A2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |