Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563315 | 0.93 | KDM4E (0.53) | DRD2CYP2D6CYP2C19CYP1A2KDM4E | |
| SCHEMBL9563189 | 0.89 | BCHE (0.57) | DRD2CYP2D6CYP2C19CYP1A2KDM4E | |
| SCHEMBL9563188 | 0.85 | DRD2 (0.53) | DRD2CYP2D6CYP2C19BCHEPARP14 | |
| SCHEMBL9563333 | 0.84 | CYP2D6 (0.60) | CYP2D6CYP2C19CYP1A2KDM4EBCHE | |
| SCHEMBL9563220 | 0.83 | CYP2D6 (0.57) | CYP2D6CYP2C19CYP1A2KDM4EBCHE | |
| SCHEMBL9563212 | 0.82 | CYP2D6 (0.55) | DRD2CYP2D6CYP2C19CYP1A2KDM4E | |
| SCHEMBL9557473 | 0.81 | DRD2 (0.48) | DRD2BCHE | |
| SCHEMBL9563238 | 0.81 | CYP2D6 (0.65) | DRD2CYP2D6CYP2C19CYP1A2KDM4E | |
| SCHEMBL12090256 | 0.81 | DRD2 (0.49) | DRD2CYP2D6CYP2C19CYP1A2BCHE | |
| SCHEMBL9563177 | 0.81 | CYP2D6 (0.53) | CYP2D6CYP2C19CYP1A2KDM4EBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |