Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563280 | 0.84 | CES2 (0.42) | MAPTTSHRCES2CES1KEAP1 | |
| SCHEMBL14033230 | 0.83 | SLC6A3 (0.42) | MAPTTSHRSLC6A3HTTNPC1 | |
| SCHEMBL7320913 | 0.82 | SLC6A3 (0.41) | MAPTTSHRTP53SLC6A3HTT | |
| SCHEMBL9563302 | 0.78 | IDO1 (0.36) | MAPTTSHRCES2CES1KEAP1 | |
| SCHEMBL9163004 | 0.77 | CYP19A1 (0.39) | MAPTTSHROPRD1LMNA | |
| SCHEMBL1537396 | 0.77 | MAPT (0.57) | MAPTTSHROPRM1OPRD1OPRK1 | |
| SCHEMBL31065464 | 0.77 | MAPT (0.57) | MAPTTSHROPRM1OPRD1OPRK1 | |
| SCHEMBL945317 | 0.76 | MAPT (0.44) | MAPTTSHROPRM1OPRD1OPRK1 | |
| SCHEMBL4167223 | 0.74 | MAPT (0.42) | MAPTTSHROPRM1OPRD1OPRK1 | |
| SCHEMBL3645137 | 0.74 | MAPT (0.46) | MAPTTSHROPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116946989-A | Preparation method of phosphane/deuterated phosphane and derivatives thereof | 北京大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-116438214-A | Sealing material for organic EL display element, cured product thereof, and organic EL display device | 三井化学株式会社 | 2023-07-14 | — | — | CN | disclosed |
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |