Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565887 | 0.97 | BCHE (0.45) | BCHEPARP14CHRM3ADRB2HTR1A | |
| SCHEMBL9563260 | 0.93 | CHRM3 (0.39) | BCHEPARP14CHRM3ADRB2HTR1A | |
| SCHEMBL9563340 | 0.92 | HTR1A (0.40) | BCHEPARP14CHRM3ADRB2HTR1A | |
| SCHEMBL9563263 | 0.89 | BCHE (0.52) | BCHEPARP14CHRM3HTR1ADRD2 | |
| SCHEMBL9563350 | 0.89 | CHRM3 (0.39) | BCHEPARP14CHRM3ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL9563254 | 0.88 | BCHE (0.51) | BCHEPARP14CHRM3HTR1ADRD2 | |
| SCHEMBL9563241 | 0.86 | BCHE (0.53) | BCHEPARP14CHRM3ADRB2HTR1A | |
| SCHEMBL9563179 | 0.86 | BCHE (0.56) | BCHEPARP14CHRM3ADRB2HTR1A | |
| SCHEMBL9563231 | 0.86 | DRD4 (0.37) | CHRM3ADRB2HTR1AHTR7LMNA | |
| SCHEMBL9563250 | 0.86 | SCN8A (0.36) | HTR1ALMNACHRM2ADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | claimed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | claimed |
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |