Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | HPD | P32754 | 2/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24405665 | 0.74 | TP53 (0.53) | NPSR1TP53ALDH1A1MAPTKDM4E | |
| SCHEMBL11422161 | 0.69 | NPSR1 (0.53) | NPSR1TP53ALDH1A1MAPTKDM4E | |
| SCHEMBL11841257 | 0.69 | TP53 (0.45) | NPSR1TP53ALDH1A1MAPTKDM4E | |
| SCHEMBL26947280 | 0.67 | NPSR1 (0.50) | NPSR1TP53ALDH1A1MAPTKDM4E | |
| SCHEMBL29485049 | 0.66 | MGLL (0.59) | NPSR1TP53ALDH1A1MAPTKDM4E | |
| SCHEMBL717739 | 0.66 | MGLL (0.59) | NPSR1TP53ALDH1A1MAPTKDM4E | |
| SCHEMBL17264593 | 0.65 | BCHE (0.53) | NPSR1TP53ALDH1A1MAPTKDM4E | |
| SCHEMBL17572311 | 0.65 | NPSR1 (0.47) | NPSR1TP53ALDH1A1MAPTKDM4E | |
| SCHEMBL13024384 | 0.64 | ADORA2A (0.41) | TP53ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL3304568 | 0.63 | ALDH1A1 (0.52) | NPSR1TP53ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543404-A1 | Stereoselective method for the industrial preparation of 5-alkyl-2'-deoxy-beta-uridines | Magyar Tudomanyos Akadémia Központi Kémiai Kutato Intézete (HU) | 1993-05-26 | — | — | EP | disclosed |