Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30402458 | 0.81 | GRM4 (0.45) | TP53ALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL15082037 | 0.76 | PGR (0.53) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL24405780 | 0.75 | CYP1A2 (0.46) | KDM4EGRM4MEN1KMT2APGR | |
| SCHEMBL21463394 | 0.75 | CYP1A2 (0.42) | TP53ALDH1A1KDM4ESMN1; SMN2GRM4 | |
| SCHEMBL9563481 | 0.74 | NPSR1 (0.51) | TP53NPSR1ALDH1A1GAAKDM4E | |
| SCHEMBL21031195 | 0.74 | ALDH1A1 (0.53) | TP53NPSR1ALDH1A1GAAKDM4E | |
| SCHEMBL23709224 | 0.71 | HTR7 (0.55) | ALDH1A1KDM4ESMN1; SMN2MAPTRAB9A | |
| SCHEMBL29798837 | 0.70 | CYP1A2 (0.55) | ALDH1A1KDM4ESMN1; SMN2NPC1MEN1 | |
| SCHEMBL474339 | 0.70 | CYP1A2 (0.55) | ALDH1A1KDM4ESMN1; SMN2NPC1MEN1 | |
| SCHEMBL6362809 | 0.70 | PGR (0.68) | ALDH1A1KDM4ESMN1; SMN2LMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774739-B1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC (JP) | 2022-05-11 | — | — | EP | disclosed |