SCHEMBL29214136

SCHEMBL29214136

C=C[Si](C)(C=C)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 4/20 0.47
NR1H3 Q13133 4/20 0.47
KIF11 P52732 3/20 0.40
TGM2 P21980 1/20 0.39
CYP1A2 P05177 1/20 0.38
AHR P35869 1/20 0.37
PTGS1 P23219 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
FBP1 P09467 1/20 0.36
NQO2 P16083 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
ORAI1 Q96D31 1/20 0.35
ORAI2 Q96SN7 1/20 0.35
ORAI3 Q9BRQ5 1/20 0.35
TRPV6 Q9H1D0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5771954 0.83 NR1H2 (0.39) NR1H2NR1H3
SCHEMBL22580535 0.83 NR1H2 (0.43) NR1H2NR1H3KIF11CYP1A2ALDH1A1
SCHEMBL29214098 0.83 NR1H2 (0.47) NR1H2NR1H3KIF11TGM2ALDH1A1
SCHEMBL30301265 0.77 TGM2 (0.46) NR1H2NR1H3KIF11TGM2CYP1A2
SCHEMBL29214160 0.77 NFE2L2 (0.38) NR1H2NR1H3TGM2PTGS1NQO2
SCHEMBL9563524 0.75 NR1H2 (0.41) NR1H2NR1H3KIF11TGM2AHR
SCHEMBL9226183 0.74 NR1H2 (0.50) NR1H2NR1H3KIF11ALDH1A1TSHR
SCHEMBL12773794 0.74 NR1H2 (0.60) NR1H2NR1H3KIF11ALDH1A1TSHR
SCHEMBL1052798 0.74 KIF11 (0.48) NR1H2NR1H3KIF11ALDH1A1TSHR
SCHEMBL10031952 0.72 AHR (0.53) NR1H2NR1H3CYP1A2AHRPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117859229-A Nonaqueous electrolyte and nonaqueous electrolyte secondary battery 信越化学工业株式会社 2024-04-09 CN disclosed