SCHEMBL9563528

SCHEMBL9563528

C=C[Si](C)(CCCCN1CC(C)OC(C)C1)c1ccccc1C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.40
LMNA P02545 1/20 0.40
ALDH1A1 P00352 4/20 0.39
TDP1 Q9NUW8 2/20 0.39
SIGMAR1 Q99720 4/20 0.38
EBP Q15125 1/20 0.37
HTT P42858 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GAA P10253 1/20 0.36
TRPV1 Q8NER1 1/20 0.36
POLB P06746 1/20 0.35
DRD2 P14416 1/20 0.35
HTR2A P28223 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9563613 0.99 KDM4E (0.39) KDM4ELMNAALDH1A1TDP1SIGMAR1
SCHEMBL9563561 0.99 KDM4E (0.39) KDM4ELMNAALDH1A1TDP1SIGMAR1
SCHEMBL9563532 0.99 KDM4E (0.39) KDM4ELMNAALDH1A1TDP1SIGMAR1
SCHEMBL9563533 0.81 SIGMAR1 (0.45) KDM4ELMNAALDH1A1TDP1SIGMAR1
SCHEMBL9563520 0.80 SIGMAR1 (0.44) KDM4ELMNAALDH1A1TDP1SIGMAR1
SCHEMBL9563628 0.80 SIGMAR1 (0.44) KDM4ELMNAALDH1A1TDP1SIGMAR1
SCHEMBL9563603 0.80 SIGMAR1 (0.44) KDM4ELMNAALDH1A1TDP1SIGMAR1
SCHEMBL9563636 0.79 LMNA (0.40) KDM4ELMNAALDH1A1TDP1SIGMAR1
SCHEMBL9563548 0.78 LMNA (0.39) KDM4ELMNAALDH1A1TDP1SIGMAR1
SCHEMBL9563580 0.78 LMNA (0.39) KDM4ELMNAALDH1A1TDP1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524829-A1 Novel silane compound, process of preparing the same and plant growth regulator containing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-01-27 EP claimed
EP-0524829-A1 Novel silane compound, process of preparing the same and plant growth regulator containing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-01-27 EP disclosed