Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2105879 | 0.82 | ALDH1A1 (0.59) | ALDH1A1GAAMAPK1HTTNPSR1 | |
| SCHEMBL3227962 | 0.81 | MAPK1 (0.55) | ALDH1A1GAAMAPK1HTTNPSR1 | |
| SCHEMBL23663086 | 0.79 | HSPB1 (0.50) | ALDH1A1GAAMAPK1HTTNPSR1 | |
| SCHEMBL7945543 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPK1HTTMAPTHPGD | |
| SCHEMBL23391581 | 0.77 | SMN1; SMN2 (0.47) | ALDH1A1MAPK1HTTMAPTHPGD | |
| SCHEMBL9572110 | 0.76 | CYP19A1 (0.39) | ALDH1A1GAAMAPTNPC1CYP1A2 | |
| SCHEMBL9617366 | 0.76 | CYP3A4 (0.48) | MAPK1MAPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL2100704 | 0.76 | ALDH1A1 (0.52) | ALDH1A1GAAMAPK1HTTNPSR1 | |
| SCHEMBL10965638 | 0.75 | MAPT (0.51) | ALDH1A1MAPK1HTTNPSR1MAPT | |
| SCHEMBL18998671 | 0.74 | MEN1 (0.51) | ALDH1A1GAAMAPK1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5271156-A | — | — | None | — | — | JP | disclosed |
| JP-H05271156-A | DIPHENOXYBENZENE DERIVATIVE AND ITS PRODUCTION | FUJI KAGAKU KOGYO KK | 1993-10-19 | — | — | JP | disclosed |