Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 8/20 | 0.43 |
| ▸ | TYMS | P04818 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564146 | 1.00 | L3MBTL1 (0.45) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9844866 | 0.93 | DHFR (0.46) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9844864 | 0.93 | DHFR (0.46) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9844792 | 0.91 | DHFR (0.43) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9844797 | 0.91 | DHFR (0.43) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9564175 | 0.84 | DHFR (0.53) | DHFRTYMS | |
| SCHEMBL9564238 | 0.83 | DHFR (0.53) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9564235 | 0.83 | DHFR (0.53) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9844760 | 0.80 | DHFR (0.44) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9844762 | 0.80 | DHFR (0.44) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549291-A1 | Thymidylate synthase inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |